儿童喘的患病率和风险因素:系统性审查和元分析
1Department of Pediatrics, Chongqing Yubei District People's Hospital, Jianshe Road, Chongqing401120, China. 547163113@qq.com.
BMC pediatrics
|January 20, 2025
概括
儿童喘影响全球10.2%的儿童. 关键的危险因素包括肥胖,父母吸烟和早产,强调需要有针对性的健康教育,以防止可改变的因素.
科学领域:
- 儿科呼吸系统医学 儿科呼吸系统医学
- 流行病学 流行病学
- 全球卫生健康 全球卫生健康
背景情况:
- 儿童喘是一个重大的全球健康问题.
- 了解其流行率和风险因素对于有效的公共卫生战略至关重要.
研究的目的:
- 系统地审查和对儿童喘的流行病学研究进行元分析.
- 估计儿童喘的全球和区域流行率.
- 确定与儿童喘相关的关键风险因素.
主要方法:
- 在PubMed,Embase和Cochrane图书馆数据库中进行全面的文献搜索,截至2023年3月31日.
- 164项涉及1,547,404名儿童的流行病学研究的元分析.
- 主要终点:儿童喘的患病率;次要终点:相关的风险因素.
主要成果:
- 在全球范围内,儿童喘的总体患病率为10.2%.
- 患病率因地区而异,大洋洲 (23%) 和北美 (13%) 的患病率较高,欧亚洲 (8%) 的患病率较低.
- 确定的危险因素包括年龄较大,男性性别,肥胖,父母吸烟,早产,剖腹产,没有母乳养,家族病史,过敏性鼻炎,湿疹,物暴露,交通密度和饮食因素.
结论:
- 儿童喘是一种普遍的疾病,具有显著的区域差异.
- 已经确定了许多可修改和不可修改的风险因素.
- 建议重点关注可预防的风险因素的健康教育,以减轻儿童喘发病率.
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