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Updated: Jun 1, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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在胃癌发生过程中,NKX6.3调节了线粒动力学和基因组稳定性

Jung Hwan Yoon1, Jeong-Kyu Kim2, Jung Woo Eun3

  • 1Department of Pathology, Functional RNomics Research Center, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, South Korea.

Cell communication and signaling : CCS
|January 20, 2025
PubMed
概括

转录因子NKX6.3对于维持胃上皮细胞的基因组稳定性至关重要. 它的耗尽会导致线粒体缺陷和基因组不稳定,这表明NKX6.3是胃癌的潜在治疗标.

关键词:
胃癌的发生 胃癌的发生基因组稳定性 基因组稳定性线粒体的完整性 线粒体的完整性在 NKX6.3 中使用.

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