在中国的学校接触者中低估了潜在结核病感染负担:一项横截面研究
Jin Yin1, Mei Wang1, Chengguo Wu1
1Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Archives of public health = Archives belges de sante publique
|January 20, 2025
概括
中国的学校结核病查显示了潜在结核病感染 (LTBI) 检测差距显著. 这凸显了社区卫生机构对结核素皮肤测试 (TST) 质量控制的潜在问题.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 诊断的准确性 诊断的准确性
背景情况:
- 之前在中国的学校结核病 (TB) 查报告了较低的结核素皮肤测试 (TST) 阳性率.
- 社区卫生机构的结核病查方法可能无法有效识别潜伏结核病感染 (LTBI).
研究的目的:
- 评估中国学校接触调查中潜伏性结核病感染 (LTBI) 检测差距.
- 为了比较专业调查和社区层面的查之间的LTBI检测率.
主要方法:
- 一项涉及中国重庆学校联系人的横截面研究 (2022年1月至2024年4月).
- 免疫诊断方法包括TST,C-TST和IGRA.
- 通过将调查结果与2021-2022年社区级数据进行比较来评估LTBI检测差距.
主要成果:
- 在6063名参与者中,TST,C-TST和IGRA分别用于4233人,1799人和31人.
- 长期创伤患病率为15.2% (TST) 和3.6% (C-TST).
- 当与社区一级的TST结果进行比较时,发现了10.3%的显著LTBI检测差距 (χ2 = 636,P < 0.001).
结论:
- 学校接触调查对于控制结核病疫情至关重要.
- 存在一个显著的LTBI检测差距,可能与社区卫生机构中低于最佳的TST质量控制有关.
- 提高TST实施质量对于在学校环境中准确识别LTBI至关重要.
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