下一代生物电子医学:为非侵入性闭环自主神经调节辩护
Imanuel Lerman1,2,3,4, Yifeng Bu5, Rahul Singh5
1Department of Electrical and Computer Engineering, University of California San Diego, Atkinson Hall, 3195 Voigt Dr., La Jolla, CA, 92093, USA. ilerman@health.ucsd.edu.
Bioelectronic medicine
|January 20, 2025
概括
生物电子医学以闭环系统进步,整合了对大脑和身体疾病的监测和神经调节. 未来的系统旨在动态调整自主神经系统功能,以实现精确的医疗保健.
科学领域:
- 生物电子医学是生物电子医学.
- 神经调节是一种神经调节.
- 自主神经系统调节自主神经系统调节
背景情况:
- 生物电子医学已经从基本的电疗法发展到复杂的闭环系统.
- 早期的创新,如起器和深度大脑刺激,为当前的技术奠定了基础.
- 本综述考察了生物电子医学的历史和技术发展轨迹.
研究的目的:
- 审查生物电子医学的进展,重点关注闭环系统.
- 为突出各种疾病的侵入性和非侵入性神经调节技术.
- 为个性化医疗保健展示闭环非侵入性自主神经调节的潜力.
主要方法:
- 审查生物电子医学的历史和技术进步.
- 重点是侵入性技术 (植入式设备) 和非侵入性方法 (聚焦超声波,自主神经学).
- 讨论闭环自主神经调节对于诸如败血症和慢性炎症等疾病.
主要成果:
- 闭环系统为治疗干预提供了变革的潜力.
- 非侵入性自主神经调节显示出治疗毒症和慢性炎症等疾病的前景.
- 开发自主神经系统调节的动态闭环系统是一个重要的机会.
结论:
- 知识缺口,包括信号噪声,信号漂移和疗法的混效应,阻碍了当前闭环自主神经调节的发展.
- 持续反和实时调整是克服这些障碍的关键.
- 下一代闭环系统是精密医学的前沿,可实现个性化和适应性治疗.
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