在内镜抗逆流症治疗后,内镜压力研究综合系统对胃食道逆流症的实用性
Kazuki Yamamoto1, Haruhiro Inoue1, Ippei Tanaka1
1Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
概括
内镜压力研究综合系统 (EPSIS) 可靠地评估内镜抗逆流疗法 (EARTh) 后胃食管逆流病 (GERD) 治疗结果. 埃普西斯显示,治疗后胃内压力和波形梯度显著改善.
科学领域:
- 胃肠病学 胃肠病学
- 医疗器械 医疗器械
- 外科手术的结果
背景情况:
- 胃食道逆流性疾病 (GERD) 的管理通常依赖于侵入性监测,如24小时阻抗-pH (MII-pH) 测试.
- 内镜抗逆流疗法 (EARTh) 对GERD有效,但治疗后的评估可能是繁的.
- 内镜压力研究综合系统 (EPSIS) 提供了一种非侵入性方法来测量胃内压力 (IGP).
研究的目的:
- 评估EPSIS作为用于评估EARTH后结果的诊断工具的实用性.
- 确定EPSIS是否可以作为GERD治疗评估的补充工具.
- 分析IGP参数和Hill's分类在EARTh.Th之后的变化.
主要方法:
- 对接受EARTh和随后的EPSIS评估的GERD患者的回顾性分析 (2018年5月 - 2024年4月).
- 使用EPSIS测量和比较EARTh前后的胃内压力 (IGP-Max) 和波形梯度.
- 根据EARTh.Th.对希尔的分类进行评估.
主要成果:
- 在对39名患者的EPSIS评估中,术后IGP-Max显著增加 (15.2至18.0mmHg,P=0.004).
- 观察到压力波形梯度的显著改善 (0.16至0.28毫米克/秒,P<0.001).
- 希尔分类在EARTh后显著改善 (平均值2.2至1.1,P<0.001).
结论:
- 埃普西斯是一个可靠的工具,用于评估EARTh在GERD患者的有效性.
- 埃普西斯显示出作为评估GERD治疗结果的额外非侵入性方法的潜力.
- 该研究支持EPSIS作为GERD管理中的一个有价值的补充诊断工具.
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