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Updated: Jun 1, 2025

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在PCDH19集群的患者衍生的iPSC模型中改变了细胞骨动力学

Rossella Borghi1, Stefania Petrini2, Valentina Apollonio2

  • 1Molecular Genetics and Functional Genomics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Frontiers in cell and developmental biology
|January 21, 2025
PubMed
概括

原始素19 (PCDH19) 功能障碍改变了细胞骨动力学,影响了神经元中的微管稳定性和聚合速度. 这一发现揭示了PCDH19-集群的新治疗点.

关键词:
由IPSC衍生的神经元.在PCDH19中,细胞骨的动力学是一种.微纤维纤维是一种微纤维.微管是微管的组成部分.神经发育的神经发育

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