用银纳米层修饰的BioHastalex,并进行热处理以获得抗菌性质
Nikola Slepičková Kasálková1, Silvie Rimpelová2, Cyril Vacek1
1Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
Heliyon
|January 21, 2025
概括
这项研究分析了BioHastalex,一种石墨烯氧化物复合物. 银涂层增强了抗菌性质,而热处理改变了纳米结构和表面化学,影响了性能.
科学领域:
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
- 表面化学 表面化学
背景情况:
- 基于氧化石墨烯 (GO) 的复合材料对生物医学应用具有前景.
- 表面特性和抗菌功效对于生物材料的开发至关重要.
- 生物Hastalex是一种基于氧化石墨烯的新型复合材料.
研究的目的:
- 为了描述BioHastalex的表面和生物相容性.
- 为了评估银 (Ag) 喷和随后的热处理对BioHastalex的影响.
- 评估修改后的BioHastalex的抗菌特性和细胞活力.
主要方法:
- 使用各种分析方法 (例如显微镜,光谱镜) 进行表面分析.
- 评估表面形态,化学和可湿性.
- 对抗菌活性和细胞活性的评估 (MRC-5,HaCaT细胞).
主要成果:
- 热处理Ag喷射的BioHastalex诱导了表面粗度和形态的纳米级显著变化.
- 银纳米层沉积改善了BioHastalex的抗菌特性,同时保持了细胞活力.
- 热处理形成了规律的纳米集群阵列,改变了表面的Ag度,并随着治疗时间的延长而降低了抗菌功效.
结论:
- 用银和受控热处理对BioHastalex的表面修改提供了一种可调节的方法,以平衡抗菌活性和生物相容性.
- 纳米结构和表面化学变化是影响这些复合材料性能的关键因素.
- 生物哈斯泰克斯 (BioHastalex),特别是与银的修饰,显示出需要抗微生物表面和良好的细胞兼容性应用的潜力.
关键词:
生物哈斯塔莱克斯公司 BioHastalex细胞相容性 细胞相容性石墨烯复合材料 石墨烯复合材料形态学 形态学 形态学纳米结构的纳米结构聚合物的稳定性 聚合物的稳定性表面化学 表面化学表面的修改是表面的修改.更多相关视频
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
10.2K
08:08Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
22.0K
相关概念视频
01:23Hand hygiene
3.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.1K
01:18Surface Membrane Barriers
1.0K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.0K
01:30Methods of Sterilization II: Chemical Methods
6.2K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
6.2K
01:29Methods of Sterilization I: Physical Methods
19.5K
As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
19.5K