生命必需8和肝功能之间的关联:一个横截面研究
Qiaoli Liang1, Menglong Zou2, Ziming Peng3
1Doumen Qiaoli Hospital of Traditional Chinese Medicine, Zhuhai, Guangdong, China.
Frontiers in nutrition
|January 21, 2025
概括
更高的生活必需品8 (LE8) 评分与更好的肝功能相关,特别是在年轻人中. 这突出了LE8作为肝脏健康和心血管健康的关键指标.
科学领域:
- 心血管健康 心血管健康
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 生活必需品8 (LE8) 评分通过八个指标来评估心血管健康.
- 肝功能对整体健康至关重要,但其与LE8的联系尚未得到充分研究.
- 共享的代谢途径需要了解心血管和肝脏健康的相互作用.
研究的目的:
- 调查LE8得分与肝功能指标之间的关联.
- 解决有关心血管和肝脏健康联系的知识差距.
- 探索这种关系中的潜在年龄特异性差异.
主要方法:
- 使用了2007-2018年国家健康和营养检查调查 (NHANES) 数据 (n=21,873).
- 将参与者分为低,中等和高LE8分数组.
- 采用多变量回归,平滑曲线拟合,值效应分析和WQS回归进行分析.
主要成果:
- 较高的LE8得分与改善的肝功能标志物 (ALT,ALT/AST比率) 有关.
- 观察到非线性关联,具有超出特定值的显著影响.
- 年轻的参与者 (<60岁) 的相关性更强;BMI,血压,葡萄糖和尼古丁暴露是关键因素.
结论:
- LE8分数与更好的肝功能有关,特别是在年轻人群中.
- LE8可以作为一种有价值的工具来识别患有肝功能障碍风险的个体.
- 进一步的研究应该探索针对心血管健康的干预措施,以获得肝脏的好处.
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