阻塞性睡眠呼吸暂停的严重程度与COVID-19结果之间的关联
Lamis Alqahtani1, Suzana Kano2, Hanaa Bokhary1
1Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
Cureus
|January 21, 2025
概括
这项研究发现,阻塞性睡眠呼吸暂停 (OSA) 严重程度或CPAP使用与COVID-19严重程度之间没有显著联系. 较高的兴奋和低氧和与中度的COVID-19结果有关.
科学领域:
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 涉及睡眠期间的呼吸道崩,可能会加剧COVID-19的严重程度.
- 以前的研究表明OSA和COVID-19严重程度增加之间存在关联,但程度尚不清楚.
研究的目的:
- 评估阻塞性睡眠呼吸暂停严重程度与COVID-19严重程度之间的关联.
- 评估持续正气道压力 (CPAP) 遵守对OSA患者COVID-19结果的影响.
主要方法:
- 在阿卜杜勒阿齐兹国王大学医院进行的一项回顾性研究,涉及62名已成年OSA患者,他们已确认感染了SARS-CoV-2.
- 收集的数据包括OSA严重性指标的多睡眠学 (PSG) 结果和COVID-19严重性分类.
- 还分析了持续正气道压力 (CPAP) 合规数据.
主要成果:
- 在OSA严重程度 (AHI,LSAT,AI,RDI) 或CPAP坚持和COVID-19结果之间没有发现显著的相关性.
- 呼吸指数 (ARI) 的较高兴奋度和SpO2<90% (T90) 的较低时间百分比与中度COVID-19严重程度相关 (p=0.046和p=0.007).
结论:
- 在OSA严重程度/治疗和COVID-19严重程度之间没有显著的相关性.
- 需要进一步的多中心研究,包括更大的人口和全面的睡眠数据,以澄清OSA-COVID-19关系,以改善患者管理.
相关概念视频
01:21Sleep Apnea
125
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
125
01:20COPD: Pathogenesis and Clinical Features
228
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
228
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K
01:17Other Pulmonary Disorders
801
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
801
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K