肺癌和心血管疾病死亡风险
Chengshi Wang1, Zhu Wang2, Jing Yang1
1Department of Breast Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.
Frontiers in cardiovascular medicine
|January 21, 2025
概括
肺癌患者面临的心血管死亡风险明显高于普通人群. 对心血管疾病的早期监测和管理对于改善肺癌患者的生存率和生活质量至关重要.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 肺癌是全球主要的死亡原因之一.
- 心血管疾病 (CVD) 是癌症患者的重要并发症.
- 与普通人群相比,肺癌患者的特定心血管死亡风险需要详细调查.
研究的目的:
- 调查肺癌患者和普通人群之间的心血管死亡风险比较.
- 为了确定特定的年龄组和时间框架,在肺癌诊断后心血管死亡风险升高.
主要方法:
- 基于人口的队列研究,利用国家癌症研究所的监测,流行病学和最终结果 (SEER) 计划的数据.
- 包括278,418名30岁以上的肺癌患者 (1990-2020年) 和匹配的一般人口队列.
- 普森回归分析用于计算心血管死亡率的发病率比率 (IRR).
主要成果:
- 与普通人群相比,肺癌患者的心血管死亡风险 (IRR 1.74,95% CI 1.71-1.77) 高出1.74倍.
- 在年轻患者 (30-79岁:IRR 2.61) 中,风险显著增加,在30-34岁年龄组 (IRR 48.93) 中达到峰值.
- 心脏病 (IRR1.79),脑血管疾病 (IRR1.52) 和其他心血管疾病的风险增加,最高风险发生在诊断后的第一个月内.
结论:
- 肺癌患者在各种心血管疾病中面临显著增加的心血管死亡风险.
- 年轻的肺癌患者和被诊断为晚期瘤的患者需要特别注意心血管健康.
- 将心血管疾病监测整合到肺癌护理方案中,对于提高患者的生存率和生活质量至关重要.
相关概念视频
02:59Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
01:25Statistical Methods for Analyzing Epidemiological Data
295
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
295
01:21Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K
01:19Psychoneuroimmunology: Diabetes and Cancer
22
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
22
01:20COPD: Pathogenesis and Clinical Features
228
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
228