相关实验视频

Updated: May 5, 2026

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment

Published on: April 20, 2018

性饮食对代谢功能障碍相关的性肝病 (MASLD) 进展的影响:随机对照试验

Sakkarin Chirapongsathorn¹, Wiwit Rintaravitoon¹, Bhagawat Tangjaturonrasme²

¹Division of Gastroenterology and Hepatology, Department of Medicine Phramongkutklao Hospital and College of Medicine Bangkok Thailand.

JGH open : an open access journal of gastroenterology and hepatology

|January 21, 2025

概括

性饮食导致显著的体重减轻,并改善了8周内患者的代谢功能障碍相关脂肪性肝病 (MASLD) 的风险因素. 然而,它并没有降低肝脏肥胖症,这表明需要对MASLD的性饮食疗效进行更长的研究.

科学领域:

肝病学肝病学是一种肝病学.
营养科学营养科学
代谢障碍代谢障碍代谢障碍

背景情况:

与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个日益严重的健康问题.
饮食很受欢迎,但它对MASLD的影响尚未通过随机对照试验得到充分证实.
之前没有任何随机对照试验 (RCT) 评估了素饮食对MASLD进展的影响.

研究的目的:

为了评估一种性饮食在改善MASLD方面的有效性.
为了比较一种性饮食与DASH饮食教育计划对MASLD的影响.
评估肝硬化和相关代谢标记物的变化.

主要方法:

进行了一项为期8周的,开放的,随机对照试验.
24名患有MASLD的患者被随机分为两组:基因饮食或DASH饮食教育.
主要结局是通过过渡性弹性素学测量肝脏肥胖症的减少.

主要成果:

两组之间没有观察到肝硬度或肥胖症的显著差异.
基因饮食组的体重减轻显著增加 (大约1. 4%的绝对差异).
腰围,血压,脂肪量,内脏脂肪,AST,甘油三和高血糖水平的改善在食组中更大.

结论:

与生活方式建议相比,基因饮食导致更大的体重减轻,并在8周内改善了一些心血管和MASLD风险因素.
在这项试验中,性饮食并没有显著减少肝硬化或改变MASLD的进展.
需要进行更长时间和更大规模的研究来证实饮食对MASLD的长期安全性和有效性.

关键词:

马斯尔德马斯尔德是什么意思基因饮食是什么基因饮食是什么与代谢功能障碍相关的脂肪性肝病.

更多相关视频

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Published on: January 7, 2019

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

相关概念视频

Overview of Lipid Metabolism

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...

Diabetic Ketoacidosis ll: Pathophysiology

Diabetic Ketoacidosis ll: Pathophysiology

Diabetic ketoacidosis (DKA) is a metabolic emergency characterized by hyperglycemia, ketonemia, and metabolic acidosis. It results from severe insulin deficiency and an excess of counterregulatory hormones, leading to uncontrolled lipolysis, ketogenesis, and widespread electrolyte and fluid disturbances.Pathophysiology The central event in DKA is a profound loss of insulin action. Without insulin, glucose uptake in insulin-dependent tissues is impaired, while hepatic glucose production...