自我报告的健康状况,持续的症状和日常活动COVID-19住院治疗2年后
Roda Alhasan1, Lena Rafsten1,2, Alexandra C Larsson1,2
1Department of Clinical Neuroscience and Rehabilitation Medicine, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Frontiers in cellular neuroscience
|January 21, 2025
概括
在COVID-19住院2年后,持续的呼吸道症状和疲劳是常见的,这会影响许多患者的功能状态. 支持和进一步的研究对于理解和治疗这些长期COVID-19影响至关重要.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 在全球范围内,COVID-19的流行病导致了数以百万计的病例,大量的个人在感染后经历了持续的症状.
- 虽然对长期COVID-19症状的研究已经存在,但对其流行率和影响的全面了解,特别是呼吸道症状和疲劳,仍然不完整.
研究的目的:
- 调查自我报告的持续性呼吸道症状和疲劳的患病率.
- 评估这些症状对COVID-19住院治疗2年后功能状态的影响.
主要方法:
- 未来的,纵向的多中心队列研究.
- 包括因COVID-19而住院的211名患者,数据收集在出院前和2年后通过问卷进行了随访.
- 分析包括根据年龄,性别和COVID-19严重程度进行群组比较,并对功能障碍进行后勤回归.
主要成果:
- 在2年的随访 (n=125) 时,69%的人报告呼吸系统症状,78%的人报告疲劳.
- 持续的呼吸道症状和疲劳显著影响了功能状态 (分别p<0.001和p=0.028).
- 根据年龄,性别或最初的COVID-19严重程度,没有发现症状流行或影响的显著差异.
结论:
- 呼吸道症状和疲劳可能在COVID-19住院后持续长达2年,无论患者的人口统计数据或最初的疾病严重程度如何.
- 对于长期出现COVID-19症状的个人来说,专业的支持是必不可少的.
- 需要进一步的研究来阐明长期症状的机制,并制定有效的干预措施.
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