患者和公众参与瑞士的学术临床研究 - - 一项混合方法研究
Deborah Eberle1,2, Annina Bauer1,3, Cordula Landgraf4
1Clinical Trials Center Zurich, University Hospital Zurich, Zurich, Switzerland.
Swiss medical weekly
|January 21, 2025
概括
瑞士临床研究中的患者和公众参与 (PPI) 被广泛接受,但在培训,资金和基础设施方面面临挑战. 需要一个协作框架来加强PPI并满足国际标准.
科学领域:
- 临床研究 临床研究
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患者和公众参与 (PPI) 对于伦理,可行和高质量的临床研究至关重要.
- 瑞士学术临床研究中PPI的现状和采用情况尚不清楚.
- 本研究涉及评估瑞士PPI的风景和接受度的必要性.
研究的目的:
- 评估PPI在瑞士学术临床研究中的当前状态和接受程度.
- 确定PPI实施的障碍和促进者.
- 为推进瑞士临床研究中的PPI制定建议.
主要方法:
- 采用了一项连续的解释性混合方法研究.
- 调查和半结构面试与各种利益相关者群体进行:患者和公众,研究人员,学术研究基础设施 (ARI) 工作人员和监管/资助机构.
- 数据分析包括调查的描述性统计数据,面试的定性分析和SWOT分析.
主要成果:
- 123个调查回复表明,所有利益相关者群体都对PPI有强烈的支持和接受.
- 确定的主要挑战包括培训不足,资金有限以及PPI的基础设施不足.
- 尽管有广泛的支持,但PPI的实际实施面临着重大障碍.
结论:
- 瑞士学术临床研究中PPI的框架正在芽.
- 所有利益相关者之间的协调努力对于与国际最佳实践保持一致至关重要.
- 建议包括建立一个基本的PPI框架,包括指导方针,最佳实践,培训和可持续融资.
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