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Updated: Jun 1, 2025

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay
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合成和描述新的 (Au,Ru和Rh) 离子复合物,并评估它们作为抗癌和抗氧化剂的活性

Abbas Ali Salih Al-Hamdani1, Fatimah Al-Zahraa Sh H2, Samara Ali Mutar3

  • 1Department of Chemistry, College of Sciences for Women, University of Baghdad, Baghdad, Iraq. abbasas_chem@csw.uobaghdad.edu.iq.

Applied biochemistry and biotechnology
|January 21, 2025
PubMed
概括

使用阿佐染料的新型金属复合物显示出显著的抗氧化和抗癌特性. 金复合物显示出对乳腺癌细胞的自由基抑制和抗癌活性最高.

关键词:
抗癌药物-MCF7 这种药物抗氧化剂是一种抗氧化剂.一个复杂的 Au 复杂.热分析是一种热分析.

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The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
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Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
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