相关实验视频
Updated: Jun 1, 2025

09:36
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
27.0K
儿童肥胖治疗对长期健康的影响
Resthie R Putri1, Pernilla Danielsson1, Nils Ekström2
1Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
JAMA pediatrics
|January 21, 2025
概括
有效的儿科肥胖治疗显著降低了2型糖尿病,高血压和年轻成年人死亡率的长期风险. 实现肥胖缓解或良好的治疗反应提供了持久的健康益处.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 关于儿童肥胖治疗结果的长期数据很少,包括死亡率.
- 了解治疗反应对年轻成年人关键健康问题的影响至关重要.
研究的目的:
- 评估不同儿童肥胖治疗反应对健康结果的长期影响,直到年轻成人.
- 分析治疗反应与肥胖相关疾病和死亡风险之间的关联.
主要方法:
- 一项动态前性队列研究,使用瑞典儿童肥胖治疗注册表 (BORIS) 和国家注册表.
- 包括患有肥胖的儿童和青少年 (6-17岁),与匹配的一般人口对照相比.
- 按体重指数标准偏差分数变化分类的治疗反应 (差,中等,好,缓解).
主要成果:
- 肥胖缓解或治疗反应良好的人群显示死亡风险显著降低 (HR,0.12).
- 良好的反应与较低的2型糖尿病 (HR,0.42),失脂症 (HR,0.31) 和减肥手术 (HR,0.42) 的风险有关.
- 肥胖缓解也降低了高血压风险 (HR,0.40);没有发现与抑郁症/焦虑症的相关性.
结论:
- 对儿科肥胖治疗的积极反应导致持续的健康优势进入年轻成人.
- 有效的治疗显著减轻了与肥胖相关的主要疾病和过早死亡的长期风险.
- 这些发现强调了优化儿童肥胖干预措施对终身健康的重要性.
相关概念视频
Obesity
372
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
372
Diabetes: Management and Pharmacotherapy
233
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
233
Insulin: Dosing Regimen and Adverse Effects
141
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
141
Stress Prevention and Stress Management Techniques IV
25
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
25
Attention-Deficit/Hyperactivity Disorder
36
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
36
Lifestyle Factors and Health
33
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
33

