注意力训练与阿片类药物使用,渴望和焦虑的恢复支持在布普伦诺芬治疗期间:一项随机临床试验
Zev Schuman-Olivier1,2, Hannah Goodman1, Joseph Rosansky1,2
1Department of Psychiatry, Cambridge Health Alliance, Malden, Massachusetts.
JAMA network open
|January 21, 2025
概括
正念训练可能有助于减少阿片类药物渴望在接受布普伦诺芬治疗阿片类药物使用障碍 (OUD) 的患者. 虽然这两组都减少了焦虑,但正念在减少残留阿片类药物渴望方面显示出显著的优势.
科学领域:
- 成 药物 药物 药物 药物
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 用布普伦诺芬治疗阿片类药物使用障碍 (OUD) 可能受到焦虑和残留阿片类药物渴望等并发症的挑战.
- 需要有效的干预措施来解决这些并发病症,并改善治疗的持续性.
- 群体干预的虚拟交付为OUD护理提供了一个可扩展的解决方案.
研究的目的:
- 为了比较正念恢复阿片类药物使用障碍护理连续 (M-ROCC) 计划与在接受布普伦诺芬治疗OUD的成年人中的活性对照的疗效.
- 评估基于正念的干预对物质使用,焦虑和阿片类药物渴望的影响.
主要方法:
- 一项为期24周的随机临床试验,涉及196名参与者,他们接受了布普伦诺芬治疗OUD.
- 参与者几乎被分配到M-ROCC正念组或时间和注意力匹配的活跃对照组.
- 主要结局是戒断,次要结局包括焦虑和阿片类药物渴望,通过自我报告和生化确认进行评估.
主要成果:
- 在非法阿片类药物,可卡因或类药物使用方面,在M-ROCC和活跃对照组之间没有观察到任何显著差异.
- 两组人都显著减少了焦虑,两组之间没有差异.
- 与活跃对照组相比,M-ROCC组在阿片类药物渴望中显示出明显更大的减少 (P=.01).
结论:
- 基于正念的干预措施,如M-ROCC,对于正在接受布普伦诺芬治疗的OUD患者来说可能是有益的,特别是在减少残留阿片类药物渴望方面.
- 正念干预的虚拟交付是OUD护理的一个可行的方法.
- 虽然干预组和对照组都减少了焦虑,但正念特别针对并减少了阿片类药物渴望.
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