针对过敏性鼻炎的不同益生菌疗法的有效性:一个网络的元分析
Chang Lu1, Yuan Gao2, Siyue Dong1
1Inner Mongolia Medical University, Hohhot, 010010, China.
Complementary therapies in clinical practice
|January 21, 2025
概括
益生菌混合物有望改善过敏性鼻炎 (AR) 症状和生活质量. 像Saccharomyces和Lactobacillus这样的特定菌株也为AR治疗提供了有针对性的好处.
科学领域:
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 过敏性鼻炎 (AR) 显著影响生活质量.
- 基于证据的治疗选择对于有效的AR管理至关重要.
- 益生菌正在被探索为AR的新治疗方法.
研究的目的:
- 评估各种益生菌物种在治疗过敏性鼻炎 (AR) 的疗效.
- 为基于证据的治疗选择益生菌为AR提供基础.
主要方法:
- 进行了网络元分析 (NMA).
- 截至2024年4月30日,搜索了9个数据库.
- 包括31个随机对照试验 (RCT),其中包括2544名AR患者.
主要成果:
- 益生菌混合物在降低鼻炎生活质量 (RQLQ) 评分和IgE水平方面最有效.
- 萨卡罗米塞斯在全鼻症状评分 (TNSS) 中显示出最大的降低,并提高了疗效率.
- 乳酸菌在降低血中乙氨基酸细胞数量方面最有效.
结论:
- 益生菌混合物为过敏性鼻炎提供了最佳的联合疗效.
- 萨卡罗米塞斯和乳酸菌在减少AR症状方面表现出特定的益处.
- 益生菌代表了对过敏性鼻炎管理的有前途的治疗选择.
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