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Updated: Jun 1, 2025

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells
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Published on: January 11, 2019

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KLF4在人类原始生殖细胞发育中的作用

Sun-Min Lee1,2, Merrick Pierson Smela1,3, M Azim Surani1,4

  • 1Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK.

Open biology
|January 21, 2025
PubMed
概括

克鲁佩尔样因子KLF4对于人类原始生殖细胞 (PGC) 的发展至关重要. KLF4促进了PGC的特异性,并抑制了体基因,确保了适当的PGC身份.

关键词:
在KLF4KLF4多能性因素是多能性的因素.原始的生殖细胞.干细胞是干细胞的组成部分.

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