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雄激素受体在黑色素瘤攻击性中的作用

Marzia Di Donato1, Costanza Maria Cristiani2, Mariaelena Capone3

  • 1Department of Precision Medicine, University of Campania 'L. Vanvitelli'- Via L. De Crecchio 7, 80138, Naples, Italy.

Cell death & disease
|January 21, 2025
PubMed
概括

雄激素受体激活促进黑色素瘤的入侵性和免疫逃避,通过触发MICA脱落. 阻断雄激素受体或ADAM10增强了自然杀手细胞的活性,并改善了黑色素瘤患者的免疫治疗反应.

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