Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

4.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
4.9K
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

2.8K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
2.8K
Electrical Energy01:10

Electrical Energy

1.2K
Using electric appliances for a longer period of time consumes more electrical energy and results in a higher electric bill. The energy produced by the transfer of electrons from one point to another is known as electrical energy. If power is delivered at a constant rate, the electrical energy can be defined as the product of power used by the device for a period of time. The energy unit on electric bills is the kilowatt-hour, where one kilowatt-hour is equivalent to 3.6 × 106 joules.
1.2K
Energy to Drive Translocation01:37

Energy to Drive Translocation

2.0K
Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
Generally, polypeptides are unfolded by two distinct...
2.0K
Van de Graaff Generator01:15

Van de Graaff Generator

1.7K
Van de Graaff generators (or Van de Graaffs) are devices used to demonstrate high voltage due to static electricity that can also be used for research. Robert Van de Graaff first built one in 1931 (based on original suggestions by Lord Kelvin) for use in nuclear physics research.
Van de Graaff uses both smooth and pointed surfaces, conductors, and insulators to generate large static charges and, hence, large voltages. A substantial excess charge can be deposited on the sphere because it moves...
1.7K
Electrical Power01:07

Electrical Power

3.0K
Electric power is the product of current and voltage, represented in units of joules per second, or watts. For example, cars often have one or more auxiliary power outlets with which you can charge a cell phone or other electronic devices. These outlets may be rated at 20 amps and 12 volts, so that the circuit can deliver a maximum power of 240 watts. Consider a 25 Watt bulb and a 60 Watt bulb. The conversion of electrical energy produces heat and light, while the kinetic energy lost by the...
3.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Electrical Forces in Biology Across Distances.

Reviews of physiology, biochemistry and pharmacology·2025
Same author

Electricity in Space and on Earth.

Reviews of physiology, biochemistry and pharmacology·2025
Same author

Electricity in the Creation of Life.

Reviews of physiology, biochemistry and pharmacology·2025
Same author

Long-Distance Electron Transport in Unicellular Organisms and Biofilms.

Reviews of physiology, biochemistry and pharmacology·2025
Same author

Multicellularity and Electrical Forces.

Reviews of physiology, biochemistry and pharmacology·2025
Same author

Epithelia Are Scaffolds for Electricity-Dependent Molecular Interactions.

Reviews of physiology, biochemistry and pharmacology·2025

相关实验视频

Updated: Jun 1, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

2.7K

SARS-CoV-2 是一种由电力驱动的病毒.

Colin D McCaig1

  • 1Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.

Reviews of physiology, biochemistry and pharmacology
|January 21, 2025
PubMed
概括

SARS-CoV-2 流行病突显了电力在生物学中的作用. 本研究研究了电相互作用,包括液体-液体相分离,如何调节关键的病毒结构蛋白.

科学领域:

  • 生物物理学的生物物理.
  • 分子生物学分子生物学
  • 病毒学 病毒学

背景情况:

  • SARS-CoV-2 流行病带来了重大的生物挑战.
  • 电力被认为是各种生物事件的无处不在的驱动因素.
  • 了解病毒蛋白的功能对于抗击流行病至关重要.

研究的目的:

  • 为了研究SARS-CoV-2结构蛋白的电调节.
  • 探索液-液相分离 (LLPS) 在病毒蛋白活性中的作用.
  • 为了将电力力量的更广泛的概念与病毒机制联系起来.

主要方法:

  • 对SARS-CoV-2结构蛋白 (尖峰,核囊,膜,信封) 的电特性进行分析.
  • 检查LLPS如何影响蛋白质功能.
  • 对驱动相分离的多价值,π-和π-π电相互作用的审查.

主要成果:

  • 电力力量在尖峰,核体,膜和包膜蛋白中起着调节作用.
  • 确定LLPS是控制这些病毒蛋白活性的关键机制.
  • 特定的电相互作用 (多价值,π-,π-π) 涉及到驱动LLPS.
关键词:
包裹蛋白质是一种包裹蛋白质.这就是LLPS.这是SARS-Cov2的结构蛋白.尖蛋白质是一种尖蛋白质.电电力是指电的电力.ππ是电力作用的电力.

更多相关视频

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
05:23

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization

Published on: December 23, 2020

6.0K
Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
10:25

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

4.5K

相关实验视频

Last Updated: Jun 1, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

2.7K
Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
05:23

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization

Published on: December 23, 2020

6.0K
Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
10:25

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

4.5K

结论:

  • 电力对SARS-CoV-2结构蛋白的功能至关重要.
  • 由特定的电相互作用驱动的LLPS是病毒的关键调节过程.
  • 这种观点通过生物物理原理扩大了对病毒机制的理解.