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Updated: Jun 1, 2025

Co-Culture and Transduction of Murine Thymocytes on Delta-Like 4-Expressing Stromal Cells to Study Oncogenes in T-Cell Leukemia
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Co-Culture and Transduction of Murine Thymocytes on Delta-Like 4-Expressing Stromal Cells to Study Oncogenes in T-Cell Leukemia

Published on: June 9, 2023

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TLE4 是TLX3在T细胞急性淋巴细胞白血病中的致癌活性抑制剂

Lukas Lauwereins1,2, Quentin Van Thillo1,2, Sofie Demeyer1,2

  • 1Department of Human Genetics, KU Leuven, Leuven, Belgium.

Leukemia
|January 21, 2025
PubMed
概括

家庭盒转录因子TLX3与FLT3信号合作,驱动T细胞急性淋巴细胞白血病 (T-ALL). TLX3抑制TLE4基因,促进T-ALL细胞生长和瘤功能.

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