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在危急病患者中低血糖和医院死亡率
Hsuan-Fan Yeh1, Wen-Cheng Chao2,3,4, Chieh-Liang Wu2,3
1Department of Internal Medicine, Taichung Veteran General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan.
低血糖或低血糖在重症患者中很常见,并显著增加死亡风险. 严重或复发的发作以及非糖尿病患者的病例特别危险.
科学领域:
- 关键护理医学 关键护理医学
- 内分泌学 在内分泌学.
- 临床研究 临床研究
背景情况:
- 严格的血糖控制在重症患者可能会增加低血糖的风险和死亡率.
- 有限的现实数据存在于低血糖的发病率和重症监护室 (ICU) 的结果.
- 这项研究通过在大型ICU队列中检查低血糖症来弥补这一差距.
研究的目的:
- 调查危急病患者低血糖的发生率.
- 为了确定与低血糖相关的危险因素.
- 检查与低血糖相关的结果,特别是死亡率.
主要方法:
- 使用台中退伍军人总医院 (2015-2020) 关键护理数据库进行的回顾性队列研究.
- 分析包括16699名入院ICU的患者,重点关注215名 (12.7%) 患有低血糖症.
- 统计分析比较了患有低血糖症和没有低血糖症患者之间的死亡率,考虑到严重程度和频率.
主要成果:
- 低血糖症发生在12.7%的重症患者中,与显著更高的医院死亡率 (48.9%与15.9%) 相关.
- 低血糖症的严重程度 (中度/严重) 和频率 (一次/多次发作) 的增加与较高的死亡率相关.
- 自发性低血糖和缺乏先前的糖尿病诊断与高死亡率有关.
结论:
- 低血糖是重症患者经常发生的情况,也是死亡的独立风险因素.
- 严重,复发性和自发性低血糖期显著增加死亡风险.
- 没有糖尿病诊断的患有低血糖症的患者面临更高的死亡负担.
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