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Updated: Jun 1, 2025

Cell Cycle-specific Measurement of γH2AX and Apoptosis After Genotoxic Stress by Flow Cytometry
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凝和ATR抑制剂协同作用,通过阻断DNA损伤反应来杀死PDAC细胞

Stefanie Höfer1, Larissa Frasch1, Sarah Brajkovic1

  • 1Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany.

Molecular systems biology
|January 21, 2025
PubMed
概括

吉姆西塔 (GEM) 加上ATR抑制剂显示出对胰腺癌的强有力的协同作用. 这种组合有效地阻断了DNA损伤的修复,为胰腺管道腺癌 (PDAC) 提供了一个有前途的新治疗策略.

关键词:
对DNA损伤的反应反应药物组合查 药物组合查激酶抑制剂 激酶抑制剂胰腺癌 胰腺癌是什么?酸蛋白组学 酸蛋白组学 酸蛋白组学

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