在甲状腺癌中通过外节延伸的粗重复性喉神经侵袭
Xin Li1, Xiang-Yun Yao2, Shi-Rong Liu2
1Department of General Surgery, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
BMC cancer
|January 21, 2025
概括
在甲状腺癌中,通过外节延伸 (ENE) 重复发生的喉神经 (RLN) 侵袭通常是无症状的. 早期超声波评估有助于在手术期间保护神经,这对声带功能至关重要.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 放射学 放射学是一门学科.
背景情况:
- 淋巴转移常见于乳头和骨髓甲状腺癌.
- 反复发生的喉神经 (RLN) 通过外节延伸 (ENE) 的入侵是不充分研究的.
- 这项研究评估了甲状腺癌中转移性淋巴结RLN入侵的特征.
研究的目的:
- 评估甲状腺癌中通过外节延伸 (ENE) 重复发作的喉神经 (RLN) 侵袭的临床和成像特征.
- 评估超声波在识别转移性淋巴结位置相对于RLN的可行性.
- 确定影响神经保存和瘤结果的因素.
主要方法:
- 对15名甲状腺癌患者进行了回顾性队列研究,这些患者患有严重的RLN入侵.
- 包括2012年1月至2024年3月期间接受治疗的患者.
- 主要终点:保存的神经的百分比;次要终点:声带功能和无复发生存率.
主要成果:
- 14例状甲状腺癌 (PTC) 和1例髓状甲状腺癌 (MTC) 病例.
- 10个右边和5个左边的RLN被ENE入侵;超声波显示节点包裹RLN与模糊的边界.
- 46.7%的瘤从上腺被剃掉;20.0%保留了RLN完整性与残留瘤;13.3%永久的声带.
结论:
- 大多数因ENE侵袭RLN的患者无症状.
- 超声波可用于评估转移性淋巴结相对于RLN的位置.
- 中心隔间评估对于神经的保存和激素切除至关重要,特别是在MTC中.
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