在中国的4538名工人中,记录了与暴露相关的并发症
Qian Hua1, Pingyang Zhang2, Yong Yang1
1Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong Institute of Occupational Health and Occupational Medicine, Jinan, 250062, China.
BMC public health
|January 21, 2025
概括
中国工人暴露于会导致广泛的并发病. 较高的血含量显著增加了以剂量依赖的方式发展多种健康状况的风险.
科学领域:
- 职业健康 职业健康 职业健康
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
背景情况:
- (Pb) 暴露对工人造成重大健康风险.
- 系统地记录暴露人群的发病率对于风险评估至关重要.
- 了解暴露和并发症之间的关系对于公共卫生至关重要.
研究的目的:
- 系统地记录中国暴露工人的病率.
- 评估血液中度 (BLC) 与并发症患病率之间的关系.
- 调查暴露和并发症风险之间的剂量反应关系.
主要方法:
- 集群采样从中国河南省的一家工厂招募了4538名暴露于的工人.
- 对每个参与者收集了发病率数据和血液度 (BLC).
- 用物流回归和受限立方线 (RCS) 模型来分析数据.
主要成果:
- 在4538名工人中,有27.4%的人患有并发病.
- 较高的BLC与伴随性疾病的1.79倍增加显著相关 (p < 0.001).
- 在BLC和并发症风险之间观察到显著的非线性剂量反应关系,女性工人表现出更高的易感性.
结论:
- 在暴露于的工人中,共患病很普遍.
- 伴随性疾病的风险取决于暴露的剂量.
- 女性工人可能更容易受到引起的并发病.
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