相关实验视频

Updated: Jun 1, 2025

Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model
12:23

Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model

Published on: April 24, 2020

19.4K

在骨关节炎发育过程中诊断和突炎中对编程细胞死亡相关基因的综合分析:基于批量和单细胞RNA测序数据

JiangFei Zhou1, SongSong Jiao1, Jian Huang2

  • 1Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People's Republic of China.

Journal of inflammation research
|January 22, 2025
PubMed
概括

这项研究确定了五个关键的编程细胞死亡 (PCD) 相关基因,这些基因与骨关节炎 (OA) 相关. 这些基因TNFAIP3,JUN,PPPP1R15A,INHBB和DDIT4显示出作为OA诊断生物标志物和治疗点的潜力.

关键词:
生物信息学是一种生物信息学.生物标志物 生物标志物免疫透 免疫透是什么?机器学习是机器学习.骨关节炎是一种关节炎.被编程的细胞死亡.

更多相关视频

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint06:06

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

5.8K
Synovial Fluid Analysis to Identify Osteoarthritis07:51

Synovial Fluid Analysis to Identify Osteoarthritis

Published on: October 20, 2022

4.2K

相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.4K
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

4.6K
The JAK-STAT Signaling Pathway01:20

The JAK-STAT Signaling Pathway

Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as  SH2...
8.6K
RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
9.8K