人类指数与成年人非酒精性脂肪肝疾病之间的关系:一个横截面研究
Mina Radmehr1, Reza Homayounfar2,3, Abolghasem Djazayery4
1Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Frontiers in nutrition
|January 22, 2025
概括
体重指数 (BMI) 和腰比身高 (WHtR) 是预测成年人非酒精性脂肪肝疾病 (NAFLD) 的最有效的非侵入性指标. 这些简单的测量为早期风险检测提供了一个实用的方法.
科学领域:
- 代谢障碍 代谢障碍 代谢障碍
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是一种与代谢综合征和心血管问题相关的普遍疾病,但认识却很低.
- 肝脏活检,诊断标准,是侵入性的和昂贵的,需要更安全的替代品.
- 早期发现NAFLD风险因素对于及时干预至关重要.
研究的目的:
- 评估各种非侵入性人体指数在预测NAFLD方面的有效性.
- 确定成年人中NAFLD最可靠和最容易获得的预测因素.
- 为了比较NAFLD查的不同人体测量措施的预测能力.
主要方法:
- 这是一项横截面研究,利用了Fasa队列中大约1万名个体的数据.
- 医生使用病史和超声波检查证实NAFLD的诊断.
- 计算和比较人类指数,包括WHR,WHtR,BMI,ABSI,BRI和VAI,以及后勤回归和ROC曲线分析.
主要成果:
- 腰与部比 (WHR),腰与身高比 (WHtR),体重指数 (BMI) 和内脏脂肪指数 (VAI) 显示与NAFLD有显著的关联.
- 在ROC分析中,WHtR和BMI被确定为两性中NAFLD最准确的预测指标.
- ABSI的预测能力很差,因此不适合用于NAFLD查.
结论:
- BMI和WHtR是最实用和最容易获得的用于早期查NAFLD男性和女性的人类指标.
- 这些指数提供了一种有价值的,非侵入性的工具,用于识别有NAFLD风险的个体.
- 进一步的研究可以探索将这些指数整合到常规健康检查中,以进行积极的NAFLD管理.
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