焦虑,抑郁和扩大残疾状况尺度独立预测多发性硬化症患者对残疾的看法:一项横截面研究
Chiara Curatoli1, Alessia Marcassoli2, Filippo Barbadoro2
1Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Behavioural neurology
|January 22, 2025
概括
焦虑和抑郁等心理因素对多发性硬化症 (MS) 患者的感知障碍有重大影响. 针对这些问题的干预措施对于改善MS患者的生活质量至关重要.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 康复医学 康复医学 康复医学
背景情况:
- 多发性硬化症 (MS) 是年轻人残疾的主要原因.
- 心理,认知和社会因素对MS主观残疾的影响仍未得到充分研究.
研究的目的:
- 研究临床,心理,认知和社会支持变量对多发性硬化症患者 (pwMS) 感知到的残疾的预测作用.
主要方法:
- 使用世界卫生组织残疾评估表2.0 (WHODAS 2.0) 对主观残疾和扩展残疾状况表 (EDSS) 对客观残疾.
- 评估焦虑和抑郁使用国家道焦虑清单和贝克抑郁清单-II.
- 用Rao的简短可重复电池评估认知功能,用医学结果研究-社会支持调查评估社会支持.
- 采用多变量回归分析,将WHODAS 2.0作为结果变量.
主要成果:
- 对象性残疾 (EDSS),状态焦虑和抑郁症状显著预测了感知到的残疾 (WHODAS 2.0分).
- 这些因素解释了主观残疾差异的很大一部分.
- 在这个群体中,认知功能和感知到的社会支持并不是感知到的残疾的独立预测因素.
结论:
- 临床和心理因素,特别是焦虑和抑郁,是pwMS中感知残疾的关键决定因素.
- 在这项研究中,认知功能和社会支持并不能独立预测主观残疾.
- 应将心理社会干预纳入多发性硬化症康复计划,以减轻感知到的残疾.
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