高度化在外周给药后的严重炎和皮肤亡:一个病例报告和血管接入管理的影响

Fang Li¹, Ting Wang¹, Ling Wang²

¹Department of Hepatobiliary Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University, Shenyang, China.

Science progress

|January 22, 2025

概括

高度的化 (KCl) 输液可能会导致严重的组织损伤,特别是在老年患者中. 仔细监测和选择部位至关重要,以防止静脉注射电解质补充期间出现炎和皮肤亡等并发症.

科学领域:

临床医学临床医学
药理学药理学是指药理学的学科.
老年病的医生老年病的医生

背景情况:

静脉补充对于管理电解质失衡至关重要.
高度化 (KCl) 输液带有外流并发症的风险,包括炎和组织亡.
由于生理变化影响组织完整性和敏感性,老年患者的风险增加.

研究的目的:

在KCl外周输液后,在老年患者中报告炎和皮肤亡病例.
为了强调在老年患者注射缩KCl时仔细选择和监测部位的重要性.
强调需要及时和多方面的管理输液相关的并发症.

主要方法:

一个病例报告详细介绍了一个老年妇女的表现,管理和结果,接受了外围6%的KCl输液.
对输液部位并发症的临床评估,包括炎和皮肤亡.
干预措施包括停药,管切除,局部硫酸,肢体升高,水凝敷料,伤口脱bridement,和物理治疗.

主要成果:

由于表面静脉部位选择和敏感性降低,患者患上了未被注意到的炎和随后的皮肤亡.
多方面的伤口管理,包括脱bridement和带,导致完整的伤口解决.
患者经历了适度的手动炼以恢复.

结论:

缩的KCl输注需要仔细选择部位和警监测,特别是在老年患者中,以防止严重的局部组织损伤.
患者特定的因素,药理风险和彻底的血管评估至关重要.
对于高风险输液,需要制定既定的方案,以预防不良事件并确保患者的安全.

关键词:

化的化物扩散.案例报告案例报告皮肤性亡 (cutaneous necrosis) 是一种皮肤性亡.皮炎 (Phlebitis) 是一种疾病.伤口清理伤口清理

相关概念视频

01:14

Prevention of Further Absorption of Poison

777

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

777

01:21

Skeletal Muscle Relaxants: Adverse Effects

332

Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...

332

01:12

Local Anesthetics: Adverse Effects

386

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

386

01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

352

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...

352

01:28

Antihypertensive Drugs: Potassium-Sparing Diuretics

442

Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...

442

01:12

Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers

895

Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium channels or enhancing inward currents from sodium channels. However, these drugs have a unique property of "reverse use-dependence," which is most pronounced at slower heart rates and can lead to torsades de pointes—a specific type of arrhythmia. However, it is essential to note that excessive QT interval prolongation—a measure of...

895