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AFFIPred:基于AlphaFold2结构的功能影响误解变化的预测

Mustafa S Pir1, Emel Timucin1,2

  • 1Department of Biostatistics and Bioinformatics, Institute of Health Sciences, Acibadem University, Atasehir, Istanbul, Turkey.

Protein science : a publication of the Protein Society
|January 22, 2025
PubMed
概括

AFFIPred利用AlphaFold2 (AF2) 预测的蛋白质结构来准确预测误解变体的致病性. 这种新的方法克服了现有方法的局限性,通过整合序列和结构数据来增强疾病预测.

关键词:
在AlphaFold2中,我们将使用AlphaFold2.错误的意义变化变化病原性分类的病原性分类.溶剂可访问的表面积面积.

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