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Updated: May 31, 2025

Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study
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脂化对葡萄糖样1的结构,氧化和聚合的影响

Eva Přáda Brichtová1,2, Irina A Edu1, Xinyang Li1

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.

Bioconjugate chemistry
|January 22, 2025
PubMed
概括

脂类葡萄糖类1 (GLP-1) 类似物显示稳定性改善,但溶解性和聚合性发生变化. 脂化部位影响寡合化和粉样蛋白形成,这对于开发长效疗法至关重要.

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