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在接受肝脏磁共振弹性成像的健康儿科群体中,脏硬

Suraj D Serai^1,2, Alexandra Glenn³, Andrew T Trout^3,4

¹Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA. serais@chop.edu.

Pediatric radiology

|January 22, 2025

概括

在健康的儿童中,通过MR弹性显微镜测量的脏硬度通常低于6.1kPa. 这种硬度测量在不同MRI供应商和场强度之间是一致的,为门高血压评估提供了可靠的参考.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
肝病学肝病学是一种肝病学.

背景情况:

骨硬是门高血压的关键成像生物标志物.
建立规范性硬度值对于准确的诊断值至关重要.

研究的目的:

为了确定健康儿童的硬度测量,使用肝脏磁共振 (MR) 弹性学.
为了评估各种MRI供应商和儿科队列中的场强度的硬度.

主要方法:

一项前性多中心横截面研究的后期分析,该研究涉及7至17.9岁的健康志愿者.
在三个供应商平台上以1.5T和3T的场强度进行MR弹性学.
脊髓硬度,长度和体积由两位独立审查员测量;统计分析包括相关性和t-test/Mann-Whitney测试.

主要成果:

在101名志愿者中,72人有可测量的硬度 (平均4.7 ± 0.9kPa;第95百分位数6.1kPa).
具有较高的审核员协同度 (ICC = 0.89). 男性志愿者表现的硬度略高于女性 (P=0.014).
脏硬与体重指数相关 (r=0.33,P=0.024) 但没有其他尺寸指标;在MRI供应商或场强度之间没有观察到显著差异.

结论:

在健康儿童中,MR弹性显微镜衍生的脏硬度低于6.1kPa.
硬度测量是可靠的,并且在这个人群中与MRI供应商或场强度没有显著差异.

关键词:

弹性图形学弹性图形学弹性图形学规范性价值是指指规范性价值.儿科儿科儿科脏脏是指脏的部分.硬性这是一种硬性.

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