卧底血压和心血管疾病和死亡率的风险
Duc M Giao1,2, Hannah Col3, Fredrick Larbi Kwapong3
1Harvard Medical School, Boston, Massachusetts.
JAMA cardiology
|January 22, 2025
概括
卧式高血压,或躺着高血压,显著增加心血管疾病 (CVD) 的风险,独立于坐着的血压. 这一发现表明,仰卧式高血压应被视为心血管疾病的独特危险因素.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 公共卫生 公共卫生
背景情况:
- 夜间高血压与心血管疾病 (CVD) 和死亡风险增加有关.
- 卧式高血压对心血管疾病风险的独立贡献,与坐姿高血压分开,尚不清楚.
研究的目的:
- 调查卧底高血压和心血管疾病结局之间的关联.
- 检查这些关联与高血压治疗状态的关系.
主要方法:
- 一项前性队列研究,利用社区动脉样硬化风险研究 (ARIC) 的数据.
- 在超过13,000名中年成人中测量了卧底和坐着的血压.
- 27年来对心血管疾病的长度监测结果,不包括先前患有心血管疾病的参与者.
主要成果:
- 在没有坐姿高血压的人群中,坐姿高血压在16.4%,坐姿高血压的人群中占73.5%.
- 高血压与发生冠心病 (CHD),心力衰竭,中风,致命性CHD和全因死亡率的风险增加有关.
- 卧式高血压的风险关联无论坐着高血压状态如何,都显著,仅卧式高血压对大多数结果的风险高于单独坐着高血压.
结论:
- 仰卧式高血压,无论坐着的高血压,与单独坐着的高血压相比,对心血管疾病风险的危险比率更高.
- 未来的研究应该在夜间高血压的背景下探索卧底高血压.
- 应考虑作为血压管理的独立目标.
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