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新诊断为淋巴瘤和骨髓瘤的患者中的焦虑和抑郁症
Oreofe O Odejide1,2, Angel M Cronin1, Tamryn F Gray1
1Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA.
Blood advances
|January 22, 2025
概括
超过一半的新诊断为淋巴瘤或骨髓瘤的患者经历了显著的焦虑和抑郁. 这些心理健康挑战会对生活质量产生负面影响,强调了早期查和支持的必要性.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 淋巴瘤和骨髓瘤的诊断给人带来了相当大的身体和心理负担.
- 关于这些患者群体中焦虑和抑郁症的患病率的数据有限.
- 早期识别心理健康问题对于全面的患者护理至关重要.
研究的目的:
- 描述最近被诊断为淋巴瘤或骨髓瘤的成年患者焦虑和抑郁症状的流行情况.
- 识别与这些症状相关的社会人口学因素.
- 检查焦虑/抑郁症状与生活质量 (QOL) 之间的关系.
主要方法:
- 在2021年7月至2022年9月期间进行了一项调查.
- 包括200名成年患者在淋巴瘤或骨髓瘤诊断后6个月内.
- 使用医院焦虑和抑郁量表来定义临床显著症状 (得分≥8).
- 多变量分析评估了与社会人口统计学,医疗不信任,财务满意度,社会支持和QOL相关的关联.
主要成果:
- 共有200名患者参与 (74.9%的应答率).
- 超过一半 (56.2%) 报告了临床显著的焦虑和/或抑郁症状.
- 在52.0%的患者中存在焦虑症状,在27.5%的患者中存在抑郁症.
- 较低的财务满意度和更高的医疗不信任与增加的焦虑有关.
- 较低的财务满意度和较低的社会支持与较高的抑郁率有关.
- 抑郁症与较低的QOL有显著的相关性 (调整后平均差异为-22.0).
结论:
- 新诊断的淋巴瘤和骨髓瘤患者经常经历显著的焦虑和抑郁.
- 财务不满,医疗不信任和低社会支持是关键的因素.
- 这些心理健康状况大大影响患者的生活质量.
- 系统的心理健康查和及时的心理干预对于这个患者群体至关重要.
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