在患有胃肠道癌的成年人中坚持口服抗癌药物:一个范围审查
Yongfeng Chen1, Marques Shek Nam Ng, Mengyue Zhang
1Author Affiliations: The Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong (Ms Chen and Drs Ng, Zhang, and Chan); and Nursing Department, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China (Ms Chen).
Cancer nursing
|January 22, 2025
概括
在胃肠道癌症患者中,口服抗癌剂 (OAA) 的坚持率很低,副作用和遗忘是关键障碍. 改善患者的支持和坚持对于更好的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在胃肠道癌症患者中,口服抗癌药物 (OAA) 的低于最佳的坚持损害了治疗疗效,增加了死亡率.
- 范围审查对于绘制OAA遵守证据和指导支持性干预措施至关重要.
研究的目的:
- 在患有胃肠道癌症的成年人中全面地图化对OAA坚持的研究.
- 为了确定合规率,不合规的原因,影响因素,管理策略和理论框架.
主要方法:
- 遵守系统审查和元分析的首选报告项目 扩展审查范围的检查清单.
- 系统地搜索7个数据库的原始研究,基于5个研究问题.
- 来自52项纳入研究的研究结果的叙述综合.
主要成果:
- 平均自我报告的遵守率为68%,范围很广 (16.7%100%).
- 常见的不坚持原因包括副作用,癌症进展,患者拒绝和遗忘.
- 在患者,疾病,治疗,社会经济和医疗保健方面确定了40多个有影响力的因素;教育和随访等管理策略显示出不一致的有效性.
结论:
- 在胃肠道癌症患者中,对OAA的坚持是不理想的,需要改善支持.
- 未来的研究应该采用严格的设计和理论框架来开发和解释增强坚持的战略.
- 建议进行常规评估和预防措施,以减轻可修改的不遵守.
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