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在后部片段的配方进展 眼部药物输送
Tumpa Sarkar1, Niva Rani Gogoi1, Bani Kumar Jana1
1Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, India.
概括
纳米结构系统为将药物输送到眼睛后部提供了一个有希望的解决方案,克服障碍并改善对视力损害疾病的治疗.
科学领域:
- 眼科和制药科学 眼科和制药科学
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
背景情况:
- 在全球范围内,后段眼部疾病是导致视力丧失的主要原因.
- 眼睛独特的屏障和快速的药物清除阻碍了有效的治疗.
- 目前的治疗方法,如内注射,有很大的缺点.
研究的目的:
- 审查用于眼睛后部疾病的纳米结构药物输送系统的最新进展.
- 探索纳米载体系统以增强视网膜向和控制药物释放.
- 突出需要创新的,最少侵入性的治疗解决方案.
主要方法:
- 对眼部药物输送系统的当前文献的综述.
- 探索各种纳米载体平台 (现场凝,体,水凝,树脂体,脂质体,纳米颗粒,纳米乳液).
- 分析克服眼障碍和改善药物透的策略.
主要成果:
- 纳米载体系统显示了改善药物输送到眼睛后部的潜力.
- 各种纳米载体系统在准视网膜和控制药物释放方面表现有前途.
- 这些系统有可能克服传统眼科疗法的局限性.
结论:
- 纳米结构药物输送系统对于推进后眼病治疗至关重要.
- 需要跨学科的方法来开发以患者为中心的,最少侵入性的眼疗法.
- 对纳米载体的进一步研究可以导致更有效和选择性的药物输送到眼睛.
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