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Updated: May 31, 2025

Conditional Genetic Transsynaptic Tracing in the Embryonic Mouse Brain
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Conditional Genetic Transsynaptic Tracing in the Embryonic Mouse Brain

Published on: December 22, 2014

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在Albumin-Cre驾驶老鼠中的多种Cre复合酶表达模式

Saeko Ishida1, Keiko Taguchi2,3, Ryuya Iida1

  • 1Division of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo.

Experimental animals
|January 22, 2025
PubMed
概括

优化Cre-driver老鼠模型对于遗传研究至关重要. 这项研究发现,插入导向和促进体起源显著影响Cre表达,指导开发更精确的肝脏特异模型.

关键词:
克雷洛克斯PPP的创作基因组编辑 基因组编辑组织学 组织学 组织学肝脏 肝脏 肝脏 肝脏 肝脏 肝脏鼠类 鼠类 鼠类 鼠类 鼠类

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Production and Titering of Recombinant Adeno-associated Viral Vectors

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Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference08:22

Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference

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相关概念视频

Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
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