参数甲状腺反量指数在韩国人中心血管风险评估中的作用
Hun Jee Choe1, Yun Mi Choi1, Yeonjung Ha2
1Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Gyeonggi-do, 18450, South Korea.
以参数性甲状腺反量基指数 (PTFQI) 衡量的下部中心甲状腺激素敏感性,与甲状腺功能良好的成年人心血管风险降低有关. 这一发现突显了特定于人群的甲状腺功能在评估心脏健康方面的重要性.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 甲状腺激素对于新陈代谢和心血管调节至关重要.
- 基于量子的参数甲状腺反指数 (PTFQI) 量化了中央甲状腺激素的敏感性.
- 评估PTFQI在心血管风险中的作用对于公共卫生至关重要.
研究的目的:
- 检查PTFQI与心血管风险之间的关联.
- 为了研究这种关系在韩国 euthyroid 人口.
主要方法:
- 利用了2013-2015年韩国国家健康和营养检查调查的数据.
- 包括5160名没有先前心血管或甲状腺疾病的轻甲状腺成年人.
- 使用PREVENT和PCE分数评估心血管风险.
主要成果:
- 较高的PTFQI四分位数与心血管疾病,动脉样性心血管疾病,心力衰竭,冠心病和缺血性中风风险降低相关.
- 在调整了各种生活方式和健康因素后,这些关联仍然很重要.
- PCE和PREVENT得分显示出强烈的正相关性.
结论:
- PTFQI与无甲状腺体个体的心血管风险相反相关.
- 降低中央甲状腺激素敏感性与较低的心血管风险有关.
- 人口特有的甲状腺功能参数对于心血管风险评估很重要.
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