前列腺癌和自杀风险:系统审查和元分析
Yun Jin Kim1, Eun Ji Lee2, Sung Ryul Shim3,4
1Department of Urology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
The world journal of men's health
|January 22, 2025
概括
患有前列腺癌的男性自杀的风险明显更高. 这项研究强调了为这些患者提供综合心理健康护理的必要性,以改善他们的福祉.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
背景情况:
- 自杀是一个主要的公共卫生问题,有各种各样的贡献因素.
- 前列腺癌是已知的自杀的危险因素在不同的人口统计学.
- 关于前列腺癌患者的自杀风险和决定因素的综合数据有限.
研究的目的:
- 与对照组相比,系统地评估和量化前列腺癌患者的自杀风险.
- 进行系统审查和元分析,以巩固现有证据.
- 确定影响这一群体自杀风险的潜在决定因素.
主要方法:
- 在PubMed,Embase和Cochrane图书馆搜索到2024年5月.
- 包括比较前列腺癌患者与对照组的研究.
- 分析了使用标准化死亡率 (SMR),相对风险 (RR) 或自杀危险率 (HR) 的结果.
- 采用随机效应模型和元回归分析.
主要成果:
- 分析了25项涉及4,987,941名参与者的研究.
- 在前列腺癌中自杀风险的聚合SMR为1.251 (95%CI:1.120-1.383).
- 自杀风险的聚合RR或HR为1.712 (95% CI:1.306-2.243).
- 统计学上显著增加的自杀风险在所有措施和分组分析中按年龄和随访期观察到.
结论:
- 前列腺癌与自杀倾向的风险增加有关.
- 综合精神和心理护理对于前列腺癌患者至关重要.
- 改善心理社会支持可以提高患者的福祉,并减轻自杀风险.
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