世卫组织关于腰围和体力活动及其与癌症风险的共同关联的指导方针
Patricia Bohmann1, Michael J Stein2, Amina Amadou3,4
1Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany patricia.bohmann@ukr.de.
British journal of sports medicine
|January 22, 2025
概括
保持健康的腰围和进行足够的体力活动对于预防癌症至关重要. 仅满足这些生活方式指南中的一个是不足以显著降低癌症风险的.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生活方式 医学 医疗
背景情况:
- 低体脂和高体力活动是已知的癌症预防策略.
- 腹部肥胖和体育活动对癌症风险的综合影响需要进一步研究.
研究的目的:
- 检查腰围和身体活动与整体癌症风险的个人和联合关联.
- 确定可归因于腹部肥胖和身体活动不足的癌症病例的比例.
主要方法:
- 利用了来自315,457名参与者的英国生物库数据.
- 根据世卫组织关于腰围和体力活动的指导方针对个人进行分类.
- 采用多变量调整的考克斯回归来估计总癌症的危险比率 (HR).
主要成果:
- 在高腰围的人群中,即使有足够的体力活动 (HR 1.11),也观察到癌症风险增加.
- 对于那些身体活动不足的人来说,即使有瘦腹部 (HR 1.04) 也注意到癌症风险增加.
- 不遵守这两条指导方针的癌症风险最高 (HR 1.15),占病例的2.0%.
结论:
- 遵守世卫组织关于腰围和身体活动的指导方针对于有效预防癌症至关重要.
- 仅满足一个指导标准 (腰围或身体活动) 不足以减轻癌症风险.
- 结合生活方式因素显著影响癌症风险,突出了综合健康策略的重要性.
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