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麻醉方法对接受内血管治疗的大型核心中风患者的结果的影响

Hongru Zhang^1,2, Xing Fang³, Mei Wu³

¹Department of Anesthesiology, Xinqiao Hospital and the Second Affiliated Hospital of Army Medical University, Chongqing, China.

Journal of neurointerventional surgery

|January 22, 2025

概括

对于接受内血管治疗的急性大核心中风患者,非全身麻醉 (非GA) 与全身麻醉 (GA) 相比,显示出类似的功能结果和安全性. 这表明非GA对于这个患者群体来说是一个可行的选择.

科学领域:

神经学神经学
麻醉学麻醉学
干预心脏病学干预心脏病学

背景情况:

在急性大核心中风中,用于内血管治疗的最佳麻醉管理尚未得到充分证实.
大型核心中风需要及时干预,使得麻醉选择对患者的结果至关重要.

研究的目的:

为了比较全身麻醉 (GA) 与非全身麻醉 (非GA) 的有效性和安全性,在接受内血管治疗的大型核心中风患者中.
根据使用的麻醉方法,评估患者的功能结果和安全终点.

主要方法:

潜在的多中心注册表的细分分析,涉及中国38个中风中心.
包括患有大核心中风的患者 (阿尔伯塔中风计划早期CT分数[方面]0-5) 在症状出现的24小时内.
主要结局:在90天后,有利的功能结局 (修改的兰金评分0-3);安全结局包括死亡率和症状性内出血.

主要成果:

总共分析了484名患者:84人 (17.4%) 接受了GA,400人 (82.6%) 接受了非GA.
在非GA和GA组之间,90天后在有利的功能结果中没有显著差异 (37.8%与32.1%;调整后的几率比率[aOR]1.07).
两组之间90天死亡率 (aOR 0.71) 和48小时症状性内出血率 (aOR 1.25) 的比较率.

结论:

这项研究发现,在大型核心中风患者的内血管治疗中,非GA和GA之间的功能结果或安全概况没有显著差异.
非全身麻醉似乎是这种特定患者群体的全身麻醉的安全有效替代方案.

关键词:

血管学血管学血管学血管整形手术是一项整形手术.血栓塞栓的情况是这样的.干预干预干预一次性中风,中风.

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