添加半基本肠道营养配方可以提高耐受性,而不会影响肠道准备质量,用于结肠镜检查:一个非劣势的随机对照试验
Nabil Mohammad Azmi1, Anith Nadzira1,2, Nur Afdzillah Abdul Rahman1
1Colorectal Unit, Department of Surgery, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, Malaysia.
World journal of surgery
|January 22, 2025
概括
低残留半元素肠道配方 (LREF) 饮食与在结肠镜检查前准备肠道的标准饮食一样有效. 这种LREF饮食改善了患者的体验,而不会影响清洁.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 医疗程序 医疗程序
背景情况:
- 传统的肠道准备通常涉及限制性饮食,长达72小时.
- 肠道准备的不愉快性质导致患者不良的服从和低于最佳的结肠清洁.
- 研究饮食修改以提高患者的耐受性和坚持肠道准备方案.
研究的目的:
- 为了比较低残留半元素肠道配方 (LREF) 合并饮食与基于聚乙烯糖醇 (PEG) 的肠道制剂标准饮食的疗效.
- 为了确定LREF饮食是否可以改善耐受性而不会影响肠道清洁.
- 评估患者的遵从性和愿意重复手术的意愿.
主要方法:
- 一个多中心,前性,单盲,随机控制的非劣等性试验.
- 167名患者被随机分配到LREF组或使用3L PEG制备方案的标准饮食 (SD) 组.
- 非劣势利率被设定为15%.
主要成果:
- 该LREF组的肠道准备质量与标准饮食组的肠道准备质量相当 (平均BPPS分数:6.87比7.14).
- 两组之间在PEG遵守,愿意重复或耐受性方面没有发现显著差异.
- 统计学上证明了肠道清洁的同等性.
结论:
- 一种低残留半元素肠道配方 (LREF) 纳入的饮食与标准饮食相等,以在基于PEG的制剂中实现令人满意的肠道清洁.
- 对于那些在长时间禁食中扎的患者,可以考虑采用LREF结合的治疗方案.
- 这种方法可以改善接受结肠镜检查的患者的手术体验.
相关概念视频
Endoscopic Procedures II: Colonoscopy
54
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
54
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
47
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
47
Lower GI Series: Barium Enema
182
A Barium Enema, or a lower GI series, is a specialized radiographic examination designed to visualize the lower gastrointestinal tract, specifically the colon and rectum. This procedure is instrumental in diagnosing various conditions such as colorectal cancer, polyps, diverticulosis, and inflammatory bowel disease.
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
182
Enteral Nutrition I: Orogastric and Nasogastric Feeding
190
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
190
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
73
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
73
Endoscopic Procedures I: Esophagogastroduodenoscopy
63
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
63


