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Updated: May 31, 2025

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用于定义和操纵干扰素诱导的Ubl蛋白酶USP1818的化学工具

Griffin J Davis1, Anthony O Omole1, Yejin Jung1

  • 1Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.

Nature communications
|January 22, 2025
PubMed
概括

研究人员开发了新的基于活动的探针 (ABP) 来检测全素特异性蛋白酶18 (USP18). 这些探测器可以选择性地检测USP18活性,有助于发现USP18抑制剂并了解它在肺癌等疾病中的作用.

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