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Updated: Jun 26, 2026

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
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Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

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两种类型的DNA回旋酶抑制剂引起了不同的进化轨迹,导致了格兰负病原体的耐药性

Semen A Leyn1, James E Kent1, Jaime E Zlamal1

  • 1Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

npj antimicrobials and resistance
|January 22, 2025
PubMed
概括

了解抗菌素耐药性机制是开发新药的关键. 这项研究表明,大肠杆菌和A. baumannii对GP6的耐药性主要涉及排泄的上调调节,与西普洛素耐药性不同.

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