在资源有限的和猪养殖环境中存在抗生素生态毒性和耐药性风险
Fredrick Gudda1,2, Dishon Muloi1,3, Fredrick Nganga1
1Animal and Human Health Programme, International Livestock Research Institute, Nairobi, Kenya.
npj antimicrobials and resistance
|January 22, 2025
概括
关于低收入国家抗菌素耐药性 (AMR) 的数据有限. 这项研究发现,三甲和硫甲对肯尼亚的农业生态系统构成风险,强调需要对环境进行监测以控制污染.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 一个健康 一个健康
背景情况:
- 抗菌素耐药性 (AMR) 是一个日益增长的全球威胁.
- 低收入和中等收入国家的农业生态系统中对抗药物耐药性的数据很少.
- 了解动物与环境通路中的抗菌耐药性对于缓解至关重要.
研究的目的:
- 调查肯尼亚农业生态系统中的AMR和抗生素污染.
- 量化与和猪养殖环境中的抗生素残留相关的风险.
- 确定影响AMR和生态毒性风险的因素.
主要方法:
- 在肯尼亚调查了52家养场和47家猪养场.
- 在环境样本中使用LC-MS/MS分析了八种常见的抗生素.
- 计算的抗生素度和AMR风险系数 (RQ).
主要成果:
- 堆肥和猪肥肥土壤显示了高抗生素流行率.
- 平均抗生素度低于环境值,除了三甲.
- 总体而言,AMR风险较低,但对于trimethoprim和sulfamethoxazole而言风险较高.
- 生态毒性和AMR风险与猪群大小和猪的抗生素使用相关.
结论:
- 在肯尼亚的农业生态系统中存在抗生素污染和AMR风险.
- 甲和硫甲醇对环境构成重大风险.
- 持续监测和大规模研究对于污染控制和AMR缓解至关重要.
更多相关视频
08:58Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
6.3K
06:57Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens
Published on: February 20, 2015
26.9K
相关概念视频
00:57Antibiotic Selection
52.2K
Overview
52.2K
01:33Bacterial Transformation
55.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
55.1K