Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pharmacodynamic Models: Overview01:27

Pharmacodynamic Models: Overview

161
Pharmacodynamic (PD) responses describe the interaction between a drug and its biological target, culminating in a physiological effect. These responses can be classified into different types: continuous variables, such as blood glucose levels; categorical outcomes, like survival rates; and time-to-event metrics, such as disease progression. Understanding and modeling PD responses are critical for optimizing drug efficacy and safety.PD models describe the relationship between drug concentration...
161
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

2.3K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
2.3K
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

79
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
79

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis.

eLife·2026
Same author

Resurfacing promotes antibacterial activity of a lipid A-binding nanobody.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

The disulfide bond formation (DSB) system: so much more than a housekeeper.

Advances in microbial physiology·2025
Same author

Disrupting iron homeostasis can potentiate colistin activity and overcome colistin resistance mechanisms in Gram-Negative Bacteria.

Communications biology·2023
Same author

Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis.

bioRxiv : the preprint server for biology·2023
Same author

Making a chink in their armor: Current and next-generation antimicrobial strategies against the bacterial cell envelope.

Advances in microbial physiology·2023

相关实验视频

Updated: May 5, 2026

Establishing the Minimal Bactericidal Concentration of an Antimicrobial Agent for Planktonic Cells MBC-P and Biofilm Cells MBC-B
06:36

Establishing the Minimal Bactericidal Concentration of an Antimicrobial Agent for Planktonic Cells MBC-P and Biofilm Cells MBC-B

Published on: January 2, 2014

19.9K

使用最小抑制度 (MIC) 测试进行抗生素敏感性测试.

Nikol Kadeřábková1, Ayesha J S Mahmood2, Despoina A I Mavridou3,4

  • 1Department of Molecular Biosciences, The University of Texas at Austin, Austin, 78712, TX, USA. nikol.kaderabkova@austin.utexas.edu.

npj antimicrobials and resistance
|January 22, 2025
PubMed
概括

本研究详细介绍了用于抗菌素敏感性测试的最小抑制度 (MIC) 测试方案. 遵循欧洲抗生素敏感性测试委员会 (EUCAST) 的指导方针,确保了对非细菌的可靠结果.

更多相关视频

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.6K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

26.0K

相关实验视频

Last Updated: May 5, 2026

Establishing the Minimal Bactericidal Concentration of an Antimicrobial Agent for Planktonic Cells MBC-P and Biofilm Cells MBC-B
06:36

Establishing the Minimal Bactericidal Concentration of an Antimicrobial Agent for Planktonic Cells MBC-P and Biofilm Cells MBC-B

Published on: January 2, 2014

19.9K
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.6K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

26.0K

科学领域:

  • 微生物学 微生物学
  • 药理学 药理学是指药理学的学科.
  • 传染性疾病 传染性疾病

背景情况:

  • 抗微生物药物耐药性 (AMR) 构成了严重的全球健康威胁,由细菌的遗传变化驱动.
  • 准确的抗微生物敏感性测试 (AST) 对于指导治疗决策和评估新抗微生物剂至关重要.
  • 最低抑制度 (MIC) 测试是确定细菌对抗生素敏感性的临床标准.

研究的目的:

  • 为执行MIC测定提供标准化的协议.
  • 将MIC测定方法与欧洲抗菌感应性测试委员会 (EUCAST) 的指导方针保持一致.
  • 支持可靠和信息丰富的MIC测试,用于研究和临床微生物学.

主要方法:

  • 详细描述MIC测定协议的详细描述.
  • 严格遵守欧洲抗菌素敏感性测试委员会 (EUCAST) 的指导方针.
  • 专注于非繁殖性细菌生物.

主要成果:

  • 建立了进行MIC测定的协议.
  • 确保与现行EUCAST对AST的标准保持一致.
  • 为可重复的MIC测试提供了一个框架.

结论:

  • 标准化的MIC测定协议对于准确的抗菌素敏感性测试至关重要.
  • 遵循EUCAST指导方针可以提高MIC测定结果的可靠性.
  • 这些协议促进了对抗菌素耐药性和药物开发的强有力的研究.