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相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

49
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
49
Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

50
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
50
Language and Cognition01:27

Language and Cognition

320
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
320

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功能,认知障碍和轨迹:一个纵向双种族研究

Katharine L Cheung1,2, Miguel Arce Renteria3, Peter W Callas4

  • 1University of Vermont College of Medicine, Burlington, VT, USA. klcheung@med.uvm.edu.

Journal of general internal medicine
|January 22, 2025
PubMed
概括

慢性病与认知能力下降有关,特别是在中年. 白膜尿加速记忆丧失,特别是在中年.

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科学领域:

  • 腎臟病學 (nephrology) 是一種醫學.
  • 神经学 神经学
  • 老年学是一门学科.

背景情况:

  • 慢性病 (CKD) 是认知障碍的重要危险因素,特别是在老年人和黑人中.
  • 了解CKD对不同年龄组和种族认知的不同影响对于有针对性的干预至关重要.

研究的目的:

  • 调查CKD和事件认知障碍 (ICI) 之间的年龄和种族特定关联.
  • 分析10年来患有和没有CKD的个体的认知轨迹.

主要方法:

  • 全国范围内对22,435名年龄在45岁及以上的黑人和白人成年人进行的队列研究,没有基线认知障碍.
  • 通过估计的膜过率 (eGFR) 和白蛋白与肌素比率 (ACR) 评估功能.
  • 认知功能使用六项选器和领域特定测试评估超过10年,分析后勤回归和潜增长曲线模型.

主要成果:

  • 慢性脏病指标 (低EGFR,高ACR) 与中年 (45-64岁) 的ICI与晚年 (≥65岁) 的ICI更强烈相关.
  • 白蛋白尿 (ACR > 300) 与较低的初始认知评分和记忆功能的急剧下降有关,特别是在中年.
  • 在CKD和认知障碍之间的关联中没有观察到任何显著的种族差异.

结论:

  • 病和认知障碍之间的关联是年龄相关的,在中年时更为强烈.
  • 白蛋白尿是认知能力下降的关键因素,特别是记忆功能,在中年人群中具有明显的影响.