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Updated: May 31, 2025

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阻断A2AR改善了阿尔茨海默病小鼠模型中的大脑输液和认知功能

Mariana Sayuri Berto Udo1, Julia Zaccarelli-Magalhães1, Garrett Alan Clemons2

  • 1Department of Neurology, McGovern Medical School, University of Texas Health Science Center, 6431 Fannin St., Houston, TX, 77030, USA.

GeroScience
|January 22, 2025
PubMed
概括

向腺素A2受体 (A2AR) 与伊斯特拉德菲林信号,改善了阿尔茨海默病 (AD) 病理的老年雌性小鼠的大脑血流和认知功能. 这种方法减少了PRMT4的表达,有利于大脑健康.

关键词:
氨酸A2受体 氨酸A2受体阿尔茨海默病 阿尔茨海默病大脑透 脑透蛋白质氨酸甲基转移酶4 蛋白质氨酸甲基转移酶4

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