内分类固醇对人类对社会相关,情感触摸的感知有所贡献
Madeleine R Jones1, Connor J Haggarty1, Gavin N Petrie2,3,4
1Department of Biomedical and Clinical Sciences, Center for Social and Affective Neuroscience, Linköping University, Linköping, Sweden.
概括
较高的安纳米德 (AEA) 水平与影响性触摸的愉悦性降低有关,这与最初的假设相反. 这一发现影响了对AEA的理解.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 社会科学 社会科学 社会科学
背景情况:
- 社会关系和情感接触对幸福至关重要.
- C-触觉 (CT) 附带器对社会相关的触觉做出反应,可能缓冲压力.
- 安纳米德 (AEA) 是一种内分泌大麻素,它会影响社会奖励和应激反应.
研究的目的:
- 调查安纳米德 (AEA) 水平与人类感知到的情感触摸的愉悦性之间的联系.
- 探索AEA在处理社会和一般情感刺激中的作用.
主要方法:
- 研究1:评估了有或没有童年虐待史的参与者的AEA水平和触摸愉悦度.
- 研究2:服用脂肪酸胺酸酸酶 (FAAH) 抑制剂以提高AEA水平或安慰剂,然后测量触摸愉悦度.
- 测量了血AEA,2-AG,皮质醇,催产素,以及自我报告的触摸和情感图像的愉悦性.
主要成果:
- 在研究1中,较高的AEA水平与对情感,CT-最佳触摸的偏好降低相关.
- 在研究2中,AEA的药理上升也导致了对情感触摸的偏好减少.
- 这些影响是特定于社交触摸处理,而不是一般的情感形象评分.
结论:
- 与假设相反,较高的AEA与情感,CT-最佳触摸的愉悦性降低有关.
- 这项研究提供了新的人类数据,将AEA与社会处理联系起来,特别是情感触觉感知.
- 结果表明AEA在社会处理中的复杂作用以及其作为社会处理障碍治疗点的潜力.
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