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Updated: May 31, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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与多结结相关的和与三结相关的发育状况-表型的融合和异质性

Alice Smail1,2,3, Reem Al-Jawahiri1, Kate Baker4,5,6

  • 1MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.

European journal of human genetics : EJHG
|January 22, 2025
PubMed
概括

在Polycomb组 (PcG) 和Trithorax组 (TrxG) 基因中的罕见变异会导致具有重叠表型的发育条件. 数据驱动的分析揭示了共同和独特的特征,突出了人类发育中的表观遗传基因调节的复杂性.

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